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Recruiting

NCT04975997: Phase 3: IberDd Versus DVd in Participants With Relapsed Refractory Myeloma - EXCALIBER

Updated: Aug 25, 2022

Open-label Study Comparing Iberdomide, Daratumumab and Dexamethasone (IberDd) Versus Daratumumab, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) (EXCALIBER-RRMM)


CC-220-MM-002

Iberdomide

This is a multicenter, randomized, controlled, open-label, Phase 3 study comparing the efficacy and safety of iberdomide in combination with dexamethasone and daratumumab (IberDd) versus daratumumab, bortezomib, and dexamethasone (DVd) in participants with relapsed or refractory multiple myeloma (RRMM).


Sponsor

Celgene


Multiple Locations

International Study

 

ClinicalTrials.gov Identifier: NCT04975997


Official Title: A Phase 3, Randomized, Multicenter, Open-label Study Comparing Iberdomide, Daratumumab and Dexamethasone (IberDd) Versus Daratumumab, Bortezomib, and Dexamethasone (DVd) in Subjects With Relapsed or Refractory Multiple Myeloma (RRMM)


First Posted : July 26, 2021


Click here to see details on ClinicalTrials.gov

 

Drug: CC-220

Drug: Dexamethasone

Drug: Daratumumab

Drug: Bortezomib

 

Locations

United States, Florida

United States, Georgia

United States, Louisiana

United States, Maryland

United States, Massachusetts

United States, Missouri

United States, New Jersey

United States, New York

United States, Ohio

United States, Pennsylvania

United States, Tennessee

United States, Texas

United States, Wisconsin

Canada

Canada, Alberta

Canada, British Columbia

Canada, New Brunswick

Canada, Newfoundland and Labrador

Canada, Nova Scotia

Canada, Ontario

Canada, Quebec

Canada, Saskatchewan

China

Europe

United Kingdom

France

Germany

Italy

Netherlands

Sweden

Austria

Belgium

Czechia

Denmark

Finland

Greece

Ireland

Norway

Poland

Portugal

Sweden

Switzerland

Turkey

Asia

Japan

Israel

Korea, Republic of

Russian Federation

Taiwan

Australia

Australia, Queensland

Australia, South Australia

Australia, Victoria

Australia, Western Australia







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