NCT04756726: Phase 1/2: CFT7455 in Relapsed/Refractory Non-Hodgkin's Lymphoma or Multiple Myeloma

Study to Assess the Safety and Tolerability of CFT7455 in Relapsed/Refractory Non-Hodgkin's Lymphoma or Multiple Myeloma

The purpose of this study is to characterize the safety, tolerability, pharmacokinetics, pharmacodynamics, and antitumor activity of CFT7455 administered orally in subjects with Relapsed/Refractory (r/r) Non-Hodgkin's Lymphoma (NHL) or Multiple Myeloma (MM) administered once a day (QD) as a single agent and in combination with dexamethasone.

Study to Assess the Safety and Tolerability of CFT7455 in Relapsed/Refractory Non-Hodgkin's Lymphoma or Multiple Myeloma

Sponsor

C4 Therapeutics, Inc

Multiple Locations

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ClinicalTrials.gov Identifier: NCT04756726

Official Title: A Phase 1/2 Open-Label Multi-Center Study to Characterize the Safety and Tolerability of CFT7455 in Subjects With Relapsed/Refractory Non-Hodgkin's Lymphoma or Multiple Myeloma

First Posted : February 16, 2021

Click here for details on ClinicalTrials.gov

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CFT7455

Cereblon E3 Ubiquitin Ligase Modulating Agent CFT7455 (Code C179502)

Cereblon E3 Ubiquitin Ligase Modulating Agent CFT7455

CFT 7455

CFT-7455

CFT7455

MonoDAC CFT7455

Monofunctional Degradation Activating Compound CFT7455

Dexamethasone

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- Arizona: Mayo Clinic Arizona

- Georgia: Emory University Atlanta

- Colorado: Sarah Cannon/Colorado Blood Cancer Institute Denver

- California: University of California San Francisco

- Florida: Mayo Clinic Jacksonville Florida

- Massachusetts: Massachusetts General Hospital Boston

- Massachusetts: Dana-Farber Cancer Institute/Harvard Cancer Center Boston

- Minnesota: Mayo Clinic Rochester Minnesota

- Missouri: Washington University School of Medicine Saint Louis

- New York: Memorial Sloan-Kettering Cancer Center New York

- New York: Tisch Cancer Institute Mount Sinai Hospital New York

- North Carolina: Levine Cancer Institute Charlotte

- Tennessee: Sarah Cannon Research Institute Nashville

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Locations

United States, Arizona

United States, California

United States, Colorado

United States, Florida

United States, Georgia

United States, Massachusetts

United States, Minnesota

United States, Missouri

United States, New York

United States, North Carolina

United States, Tennessee

United States, Wisconsin