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![MD ANDERSON multiple myeloma trials](https://static.wixstatic.com/media/cd6738_cab0bec81e944e8085917bd85520ad21~mv2.jpeg/v1/fill/w_382,h_290,al_c,q_80,usm_0.66_1.00_0.01,enc_avif,quality_auto/MD%20ANDERSON%20multiple%20myeloma%20trials.jpeg)
![NCT04270409](https://static.wixstatic.com/media/cd6738_ba8218be45c041dea68eb1a1376394a5~mv2.webp/v1/fill/w_980,h_656,al_c,q_85,usm_0.66_1.00_0.01,enc_avif,quality_auto/cd6738_ba8218be45c041dea68eb1a1376394a5~mv2.webp)
NCT04270409
![NCT04879043](https://static.wixstatic.com/media/cd6738_400801fbe1ff46bea299a74c32f0ff4f~mv2.webp/v1/fill/w_980,h_654,al_c,q_85,usm_0.66_1.00_0.01,enc_avif,quality_auto/cd6738_400801fbe1ff46bea299a74c32f0ff4f~mv2.webp)
NCT04879043
![ORIC-533](https://static.wixstatic.com/media/cd6738_97f9d7ba3ced49c3af03b60cb2d6ea7b~mv2.png/v1/fill/w_980,h_661,al_c,q_90,usm_0.66_1.00_0.01,enc_avif,quality_auto/cd6738_97f9d7ba3ced49c3af03b60cb2d6ea7b~mv2.png)
ORIC-533
![NCT04270409](https://static.wixstatic.com/media/cd6738_ba8218be45c041dea68eb1a1376394a5~mv2.webp/v1/fill/w_980,h_656,al_c,q_85,usm_0.66_1.00_0.01,enc_avif,quality_auto/cd6738_ba8218be45c041dea68eb1a1376394a5~mv2.webp)
NCT04270409
1/32
Multiple Myeloma Clinical Trials - Currently Recruiting
![Phase 2: A Study of JNJ-68284528 Out-of-Specification (OOS) for Commercial Release](https://static.wixstatic.com/media/cd6738_e6d10ae90caa46bfba984d5da74f1d46~mv2.webp/v1/fill/w_319,h_318,q_90/cd6738_e6d10ae90caa46bfba984d5da74f1d46~mv2.webp)
2022 - (R) NCT05347485
Phase 2: A Study of JNJ-68284528 Out-of-Specification (OOS) for Commercial Release
![NCT05336383: Phase 2: Phase II Study of Salvage Radiation Treatment After BCMA CART Therapy for RRMM](https://static.wixstatic.com/media/cd6738_d925175dcc304b93890c0cd673425127~mv2.webp/v1/fill/w_319,h_318,q_90/cd6738_d925175dcc304b93890c0cd673425127~mv2.webp)
2022 - (R) NCT05336383
Phase 2: Phase II Study of Salvage Radiation Treatment After BCMA CART Therapy for RRMM
![Phase 1: A Study in Subjects With Relapsed/Refractory Multiple Myeloma and RR DLBCL](https://static.wixstatic.com/media/cd6738_6311b3c2644b46e3a00a7f42cf0771ae~mv2.webp/v1/fill/w_318,h_318,q_90/cd6738_6311b3c2644b46e3a00a7f42cf0771ae~mv2.webp)
2021 - (R) NCT05121103
Phase 1: A Study in Subjects With Relapsed/Refractory Multiple Myeloma and RR DLBCL
![NCT05064787: Evaluating the Feasibility of a Digital Health Coaching Program Post CART](https://static.wixstatic.com/media/cd6738_60477a9a31884943b6037fc86103036a~mv2.webp/v1/fill/w_319,h_318,q_90/cd6738_60477a9a31884943b6037fc86103036a~mv2.webp)
2021 - (R) NCT05064787
Evaluating the Feasibility of a Digital Health Coaching Program Post CART
![NCT05000450: Phase 1/2: Safety and Efficacy of ALLO-605 an Anti-BCMA Allogeneic CAR T Cell RRMM](https://static.wixstatic.com/media/cd6738_38d94eb8743344758bbf107dde5c38cc~mv2.webp/v1/fill/w_319,h_318,q_90/cd6738_38d94eb8743344758bbf107dde5c38cc~mv2.webp)
2021 - (R) NCT05000450
Phase 1/2: Safety and Efficacy of ALLO-605 an Anti-BCMA Allogeneic CAR T Cell RRMM
![NCT04879043: Phase 1/2: Study to Assess Safety of HDP-101 in Patients With RRMM](https://static.wixstatic.com/media/cd6738_400801fbe1ff46bea299a74c32f0ff4f~mv2.webp/v1/fill/w_318,h_318,q_90/cd6738_400801fbe1ff46bea299a74c32f0ff4f~mv2.webp)
2021 - (R) NCT04879043
Phase 1/2: Study to Assess Safety of HDP-101 in Patients With RRMM
![NCT04855136: Phase 1/2 - Safety and Efficacy of bb2121 (Ide-cel) Combinations in MM (KarMMa-7)](https://static.wixstatic.com/media/cd6738_cbfc511e1ecc49f482f8c0624ef47f61~mv2.webp/v1/fill/w_319,h_318,q_90/cd6738_cbfc511e1ecc49f482f8c0624ef47f61~mv2.webp)
2021 - (R) NCT04855136
Phase 1/2 - Safety and Efficacy of bb2121 (Ide-cel) Combinations in MM (KarMMa-7)
![NCT04614636: FT538 in Subjects With Advanced Hematologic Malignancies](https://static.wixstatic.com/media/cd6738_a5d425131a7e462b9b62aa0c4b8ba995~mv2.webp/v1/fill/w_319,h_318,q_90/cd6738_a5d425131a7e462b9b62aa0c4b8ba995~mv2.webp)
2020 - (R) NCT04614636
FT538 in Subjects With Advanced Hematologic Malignancies
![NCT04582539: Phase 1/2: Safety and Tolerability of INCB000928 in Myelodysplastic Synd. or Myeloma](https://static.wixstatic.com/media/cd6738_24d1c0cef4144302ad5552a72366ea1c~mv2.webp/v1/fill/w_318,h_318,q_90/cd6738_24d1c0cef4144302ad5552a72366ea1c~mv2.webp)
2020 - (R) NCT04582539
Phase 1/2: Safety and Tolerability of INCB000928 in Myelodysplastic Synd. or Myeloma
![NCT04354246: COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies](https://static.wixstatic.com/media/cd6738_8b39f1cc020d4193a2aad0bc81b49618~mv2.webp/v1/fill/w_319,h_318,q_90/cd6738_8b39f1cc020d4193a2aad0bc81b49618~mv2.webp)
2020 - (R) NCT04354246
COM902 (A TIGIT Inhibitor) in Subjects With Advanced Malignancies
![NCT04171843: Phase 1/2: Allogeneic anti-BCMA CAR T cells PBCAR269A With or Without Nirogacestat RRMM](https://static.wixstatic.com/media/cd6738_1a351a55e95e45c9b7f887d495468b9a~mv2.webp/v1/fill/w_319,h_318,q_90/cd6738_1a351a55e95e45c9b7f887d495468b9a~mv2.webp)
2019 - (R) NCT04171843
Phase 1/2: Allogeneic anti-BCMA CAR T cells PBCAR269A With or Without Nirogacestat RRMM
![NCT04142619: Phase 1 - UCART Targeting CS1 - allogenic T cells with anti- CS1 CAR - RRMM (MELANI-01)](https://static.wixstatic.com/media/cd6738_e9c5d5876c1d4c0cb678bc004eb9ea9f~mv2.webp/v1/fill/w_318,h_318,q_90/cd6738_e9c5d5876c1d4c0cb678bc004eb9ea9f~mv2.webp)
2019 - (R) NCT04142619
Phase 1 - UCART Targeting CS1 - allogenic T cells with anti- CS1 CAR - RRMM (MELANI-01)
![NCT03997968: Phase 1/2: A Phase 1/2 Study of CYT-0851, Oral RAD51 Inhibitor, in B-Cell Malignancies](https://static.wixstatic.com/media/cd6738_09f13156946b4f5ab63c8b8813f41f89~mv2.webp/v1/fill/w_319,h_318,q_90/cd6738_09f13156946b4f5ab63c8b8813f41f89~mv2.webp)
2019 - (R) NCT03997968
Phase 1/2: A Phase 1/2 Study of CYT-0851, Oral RAD51 Inhibitor, in B-Cell Malignancies
![NCT03989414:Phase 1/2 - A Study of CC-92480 With Standard Treatments in Relapsed & New MM - MM-002](https://static.wixstatic.com/media/cd6738_1fefd1f6110b4b1baf22091c0fa80116~mv2.webp/v1/fill/w_319,h_318,q_90/cd6738_1fefd1f6110b4b1baf22091c0fa80116~mv2.webp)
2019 - (R) NCT03989414
Phase 1/2 - A Study of CC-92480 With Standard Treatments in Relapsed & New MM - MM-002
![NCT03915184: Phase 1 - Clinical Trial to Evaluate CT053 in Patients With Relapsed and/or Refractory](https://static.wixstatic.com/media/cd6738_23f775ec722d4cc99e423da34ae50709~mv2.webp/v1/fill/w_318,h_318,q_90/cd6738_23f775ec722d4cc99e423da34ae50709~mv2.webp)
2019 - (R) NCT03915184
Phase 1 - Clinical Trial to Evaluate CT053 in Patients With Relapsed and/or Refractory
![NCT03984097: Phase 1: A Study to Evaluate Subcutaneous TAK-079 Added to Standard Regimens NDMM](https://static.wixstatic.com/media/cd6738_83376d663a1c49f19e26fabd7458478a~mv2.webp/v1/fill/w_319,h_318,q_90/cd6738_83376d663a1c49f19e26fabd7458478a~mv2.webp)
2019 - (Active) NCT03984097
Phase 1: A Study to Evaluate Subcutaneous TAK-079 Added to Standard Regimens NDMM
![NCT03761108: Phase 1/2 - REGN5458 (Anti-BCMA x Anti-CD3 Bispecific Antibody) in Refractory MM](https://static.wixstatic.com/media/cd6738_52b3d51fb79e46cdbd67534ff18fcb83~mv2.webp/v1/fill/w_319,h_318,q_90/cd6738_52b3d51fb79e46cdbd67534ff18fcb83~mv2.webp)
2018 - (R) NCT03761108
Phase 1/2 - REGN5458 (Anti-BCMA x Anti-CD3 Bispecific Antibody) in Refractory MM
![NCT03601078: Phase 2 -Efficacy and Safety of bb2121 in relapsed MM & in high risk Myeloma (KarMMa-2)](https://static.wixstatic.com/media/cd6738_0b89ef259e19499b8173df2ea250de6e~mv2.webp/v1/fill/w_318,h_318,q_90/cd6738_0b89ef259e19499b8173df2ea250de6e~mv2.webp)
2018 - (R) NCT03601078
Phase 2 -Efficacy and Safety of bb2121 in relapsed MM & in high risk Myeloma (KarMMa-2)
![NCT03530683: Phase 1: A Trial of TTI-622 in Patients With Advanced Hem. Malignancies (TTI-622-01)](https://static.wixstatic.com/media/cd6738_9300654834454415aefd83474cf376e6~mv2.webp/v1/fill/w_319,h_318,q_90/cd6738_9300654834454415aefd83474cf376e6~mv2.webp)
2018 - (R) NCT03530683
Phase 1: A Trial of TTI-622 in Patients With Advanced Hem. Malignancies (TTI-622-01)
![NCT03374085: Phase 1/2: CC-92480 Monotherapy and with Dex in Relapsed / Refractory Multiple Myeloma](https://static.wixstatic.com/media/cd6738_576733f2b20441d6b2b8453502fc0521~mv2.jpg/v1/fill/w_319,h_318,q_90/cd6738_576733f2b20441d6b2b8453502fc0521~mv2.jpg)
2017 - (R) NCT03374085
Phase 1/2: CC-92480 Monotherapy and with Dex in Relapsed / Refractory Multiple Myeloma
![NCT03287908: Phase 1/2: AMG 701 Montherapy With Pomalidomide +/- Dex in Relapsed Multiple Myeloma](https://static.wixstatic.com/media/cd6738_3314cfe1b8df47199a07d57997ce01ab~mv2.webp/v1/fill/w_318,h_318,q_90/cd6738_3314cfe1b8df47199a07d57997ce01ab~mv2.webp)
2017 - (R) NCT03287908
Phase 1/2: AMG 701 Montherapy With Pomalidomide +/- Dex in Relapsed Multiple Myeloma
![NCT03275103: Phase 1 - Dose-Escalation Study of Cevostamab in Participants With RRMM](https://static.wixstatic.com/media/cd6738_92849932092541dd8f2fb86faa612ce2~mv2.webp/v1/fill/w_319,h_318,q_90/cd6738_92849932092541dd8f2fb86faa612ce2~mv2.webp)
2017 - (R) NCT03275103
Phase 1 - Dose-Escalation Study of Cevostamab in Participants With RRMM
![NCT03288493: Phase 1/2 - P-BCMA-101 Tscm CAR-T Cells in the Treatment of Patients With Myeloma](https://static.wixstatic.com/media/cd6738_94b6d7ccc5e145b19fa91a8ed1da43eb~mv2.webp/v1/fill/w_319,h_318,q_90/cd6738_94b6d7ccc5e145b19fa91a8ed1da43eb~mv2.webp)
2017 - (Completed) NCT03288493
Phase 1/2 - P-BCMA-101 Tscm CAR-T Cells in the Treatment of Patients With Myeloma
NDMM
![NCT04268498: Phase2 - Daratumumab, Carfilzomib, Lenalidomide, Dex NDMM Multiple Myeloma (ADVANCE)](https://static.wixstatic.com/media/cd6738_9a43522f557c462e9cf5567a91a645b0~mv2.jpg/v1/fill/w_319,h_318,q_90/cd6738_9a43522f557c462e9cf5567a91a645b0~mv2.jpg)
2020 - (R) NCT04268498
Phase2 - Daratumumab, Carfilzomib, Lenalidomide, Dex NDMM Multiple Myeloma (ADVANCE)
![NCT04071457: Phase 3: S1803, Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maint. NDMM DRAMMATIC](https://static.wixstatic.com/media/cd6738_c9bb818c0b7d4b4e96bd54452d9f6f53~mv2.png/v1/fill/w_319,h_318,q_90/cd6738_c9bb818c0b7d4b4e96bd54452d9f6f53~mv2.png)
2019 - (R) NCT04071457
Phase 3: S1803, Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maint. NDMM DRAMMATIC
![NCT03989414: Phase 1/2 - A Study of CC-92480 With Standard Treatments in Relapsed & New MM - MM-002](https://static.wixstatic.com/media/cd6738_1fefd1f6110b4b1baf22091c0fa80116~mv2.webp/v1/fill/w_318,h_318,q_90/cd6738_1fefd1f6110b4b1baf22091c0fa80116~mv2.webp)
2019 - (R) NCT03989414
Phase 1/2 - A Study of CC-92480 With Standard Treatments in Relapsed & New MM - MM-002
![NCT03901963: Phase 3 - Dara + Len vs Len as Maint. in New Myeloma +MRD after frontline ASCT (AURIGA)](https://static.wixstatic.com/media/cd6738_75634a9117cc4dfd80a716768da5926d~mv2.png/v1/fill/w_319,h_318,q_90/cd6738_75634a9117cc4dfd80a716768da5926d~mv2.png)
2019 - (R) NCT03901963
Phase 3 - Dara + Len vs Len as Maint. in New Myeloma +MRD after frontline ASCT (AURIGA)
MGUS/SMM
![NCT05136807: Quality of Life in Patients With Asymptomatic Monoclonal Gammopathies](https://static.wixstatic.com/media/cd6738_14e53bf91836493eba5b72dc080c81f9~mv2.webp/v1/fill/w_319,h_318,q_90/cd6738_14e53bf91836493eba5b72dc080c81f9~mv2.webp)
2021 - (R) NCT05136807
Quality of Life in Patients With Asymptomatic Monoclonal Gammopathies
![NCT04512235: Phase 3: To Evaluate Effectiveness & Safety of CAEL-101 in Stage IIIa AL Amyloidosis](https://static.wixstatic.com/media/cd6738_6e45e5a91f884167850cb2a2621de099~mv2.webp/v1/fill/w_319,h_318,q_90/cd6738_6e45e5a91f884167850cb2a2621de099~mv2.webp)
2020 - (R) NCT04512235
Phase 3: To Evaluate Effectiveness & Safety of CAEL-101 in Stage IIIa AL Amyloidosis
![NCT04504825: Phase 3: Efficacy & Safety of CAEL-101 in Patients With Mayo Stage IIIb AL Amyloidosis](https://static.wixstatic.com/media/cd6738_285b8799eb8740888702b542c65e3f35~mv2.webp/v1/fill/w_318,h_318,q_90/cd6738_285b8799eb8740888702b542c65e3f35~mv2.webp)
2020 - (R) NCT04504825
Phase 3: Efficacy & Safety of CAEL-101 in Patients With Mayo Stage IIIb AL Amyloidosis
![NCT04270409: Phase 3 - Isatuximab in Combination With Lenalidomide and Dex High-risk SMM (ITHACA)](https://static.wixstatic.com/media/cd6738_ba8218be45c041dea68eb1a1376394a5~mv2.webp/v1/fill/w_319,h_318,q_90/cd6738_ba8218be45c041dea68eb1a1376394a5~mv2.webp)
2020 - (R) NCT04270409
Phase 3 - Isatuximab in Combination With Lenalidomide and Dex High-risk SMM (ITHACA)
![NCT03937635: Phase 3 - Lenalidomide, Dex +/- Daratumumab in High-Risk Smoldering Myeloma DETER-SMM](https://static.wixstatic.com/media/cd6738_d3001c90758a4ff9b44fb98a7478cde9~mv2.png/v1/fill/w_319,h_318,q_90/cd6738_d3001c90758a4ff9b44fb98a7478cde9~mv2.png)
2019 - (R) NCT03937635
Phase 3 - Lenalidomide, Dex +/- Daratumumab in High-Risk Smoldering Myeloma DETER-SMM
![NCT03631043: Phase 1 - Personalized Vaccine in Treating Participants With Smoldering MM](https://static.wixstatic.com/media/cd6738_6a417a0f2ebc4348b79cb9b6eee19a99~mv2.jpg/v1/fill/w_318,h_318,q_90/cd6738_6a417a0f2ebc4348b79cb9b6eee19a99~mv2.jpg)
2018 - (R) NCT03631043
Phase 1 - Personalized Vaccine in Treating Participants With Smoldering MM
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